The Science

The Science Behind GHK-Cu

An ingredient with decades of scientific interest in skin appearance and cosmetic formulation.

What is GHK-Cu?

GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper) is a naturally occurring copper-binding tripeptide first identified in the 1970s. It has remained a well-known ingredient in advanced skincare research and formulation, particularly in discussions around skin appearance, visible texture, and cosmetic support for overall skin quality.

What research has explored

Research into GHK-Cu has investigated its role in supporting the appearance of:

• Smoother-looking skin
• More refined-looking texture
• Improved visible hydration
• A brighter, more even-looking complexion
• Skin that appears firmer and more refreshed over time

Why it remains relevant

GHK-Cu continues to attract attention in skincare because of its long-standing association with cosmetic research into skin appearance. Its continued use in advanced formulations reflects ongoing interest in copper peptides as part of modern topical skincare.

Why concentration matters

Concentration is an important part of how a formula is built and positioned. Cupréa is formulated with 3% GHK-Cu as its hero active, supported by a carefully considered multi-active complex.

The Cupréa approach

Cupréa combines Copper Tripeptide-1 with supporting actives to create a precision formula designed for modern luxury skincare — where advanced formulation and product experience are considered together.

A precision topical formula built around advanced copper peptide skincare.